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Generation of eight human induced pluripotent stem cells lines from patients with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS).

Stem cell research - 1 Mar 2026

Martineau Laurie, Roy Vincent, Bellenfant Sabrina, Blais Mathieu, Gros-Louis François, Dupré Nicolas

Abstract excerpt

Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited neurodegenerative disorder causing progressive spasticity, ataxia and peripheral neuropathy, leading to significant motor and sensory impairments. To advance the study of ARSACS pathogenesis and therapeutic development, we generated eight induced pluripotent stem cell (iPSC) lines from patient-derived fibroblasts or peripheral...

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Identifiers

PMID: 41529449
DOI: 10.1016/j.scr.2025.103894

Genes

SACS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Generation of eight human induced pluripotent stem cells lines from patients with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS).PMID 41529449Read ↗

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