Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammatory Proteins Mediate the Causal Association between Sleep Traits and Breast Cancer: A Mendelian Randomization Study.

Lifestyle genomics - 1 Jan 2026

Zhou Jiawei, Mao Lijun

Abstract excerpt

INTRODUCTION: Breast cancer (BC) is the most frequent cancer in women, driven by a combination of genetic, environmental, and lifestyle factors. Whether modifiable sleep behaviors causally affect BC risk remains unclear. Aims of the study were to systematically assess the causal impact of sleep-related phenotypes on overall BC and its major subtypes using two-sample mendelian randomization (MR) and to determine...

Topics

Join the communities discussing this publication.

Breast Neoplasms
Mendelian Randomization Analysis
Phenotype
Polymorphism, Single Nucleotide
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 41528935
DOI: 10.1159/000550315
PMCID: PMC12923251

Genes

CXCL11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammatory Proteins Mediate the Causal Association between Sleep Traits and Breast Cancer: A Mendelian Randomization Study.PMID 41528935Read ↗

Causal relationships between sleep duration and risk of breast tumors: A two-sample bi-directional Mendelian randomization studySemantic proximity Read ↗

Sleep traits and breast cancer risk: a two-sample Mendelian randomization study.Semantic proximity Read ↗

A two-sample Mendelian randomization analysis: causal association between chemokines and pan-carcinomaSemantic proximity Read ↗

Mendelian randomization analyses of 23 known and suspected risk factors and biomarkers for breast cancer overall and by molecular subtypes.Semantic proximity Read ↗

The Impact of Sleep on Breast Cancer-Specific Mortality: A Mendelian Randomisation StudySemantic proximity Read ↗

Causal Associations of Sleep Traits with Cancer Incidence and MortalitySemantic proximity Read ↗

Investigating the causal linkages between circulating inflammatory proteins and breast cancer risk and prognosis: Insights from a two-sample Mendelian randomization analysis.Semantic proximity Read ↗

The causal role of plasma metabolites in breast cancer susceptibility mediated by immune cells: A two-sample Mendelian randomization analysis.Semantic proximity Read ↗

The Relationship between Modifiable Lifestyle Factors and Breast Diseases: A Mendelian Randomization StudySemantic proximity Read ↗

Sleep duration and risk of overall and 22 site-specific cancers: A Mendelian randomization study.Semantic proximity Read ↗

The association between plasma chemokines and breast cancer risk and prognosis: A Mendelian randomization studySemantic proximity Read ↗

Obstructive sleep apnea syndrome and causal relationship with female breast cancer: a mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.