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Article

Inflammatory Proteins Mediate the Causal Association between Sleep Traits and Breast Cancer: A Mendelian Randomization Study.

Lifestyle genomics - 1 Jan 2026

Zhou Jiawei, Mao Lijun

Abstract excerpt

INTRODUCTION: Breast cancer (BC) is the most frequent cancer in women, driven by a combination of genetic, environmental, and lifestyle factors. Whether modifiable sleep behaviors causally affect BC risk remains unclear. Aims of the study were to systematically assess the causal impact of sleep-related phenotypes on overall BC and its major subtypes using two-sample mendelian randomization (MR) and to determine...

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Identifiers

PMID: 41528935
DOI: 10.1159/000550315
PMCID: PMC12923251

Genes

CXCL11

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