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Article

Genetic heritage of war: exploring transgenerational inheritance of PTSD and its molecular background.

Mammalian genome : official journal of the International Mammalian Genome Society - 12 Jan 2026

Džaferović Nerma, Ašić Adna

Abstract excerpt

This review article summarizes the available data about the potential link between war-related trauma and post-traumatic stress disorder (PTSD) and epigenetic alterations that could manifest in future generations. DNA methylation variations in stress-related genes such FKBP5, NR3C1, NR3C2, BDNF, and SLC6A4 have been seen in parents and/or their offspring in populations exposed to genocide, conflict, or combat....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41526709
DOI: 10.1007/s00335-025-10192-2

Genes

BDNF
FKBP5
NR3C1
NR3C2
SLC6A4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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