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Article

Nonvisceral YAP1::TFE3- Rearranged Inflammatory Spindle Cell PEComa in Somatic Soft Tissue : Clinicopathologic and Molecular Analysis of 3 Cases.

The American journal of surgical pathology - 1 Apr 2026

Malik Abdalla, Zhang Gloria, Fritchie Karen, Dermawan Josephine K

Abstract excerpt

Inflammatory spindle cell PEComa is a rare PEComa variant with rare cases harboring YAP1::TFE3 fusion recently reported in the lungs. These tumors share identical YAP1::TFE3 fusion breakpoints and overlapping morphology with clear cell stromal tumor of the lung ( CCST-L ), but differ by demonstrating a myomelanocytic immunophenotype. We report the first 3 nonvisceral cases of inflammatory spindle cell PEComa with...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41521327
DOI: 10.1097/PAS.0000000000002509

Genes

YAP1
ALK
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Nonvisceral YAP1::TFE3- Rearranged Inflammatory Spindle Cell PEComa in Somatic Soft Tissue : Clinicopathologic and Molecular Analysis of 3 Cases.PMID 41521327Read ↗

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