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Do Akkermansia mutants underlie the global metabolic disease epidemic?

Gut microbes - 31 Dec 2026

Kim Heenam Stanley

Abstract excerpt

Antibiotic-induced mutations in Akkermansia muciniphila promote bacterial survival while compromising beneficial host interactions, revealing a potential new link between antibiotic-driven microbiome disruption and metabolic disease. The widespread presence of these mutants suggests that they may contribute to the increasing prevalence of metabolic disorders. If validated in diverse global human cohort studies,...

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Identifiers

PMID: 41503894
DOI: 10.1080/19490976.2025.2612582
PMCID: PMC12785186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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