Article
Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly.
Genome biology - 14 Jul 2021
Karcher Nicolai, Nigro Eleonora, Punčochář Michal, Blanco-Míguez Aitor, Ciciani Matteo, Manghi Paolo, Zolfo Moreno, Cumbo Fabio, Manara Serena, Golzato Davide, Cereseto Anna, Arumugam Manimozhiyan, Bui Thi Phuong Nam, Tytgat Hanne L P, Valles-Colomer Mireia, de Vos Willem M, Segata Nicola
Abstract excerpt
BACKGROUND: Akkermansia muciniphila is a human gut microbe with a key role in the physiology of the intestinal mucus layer and reported associations with decreased body mass and increased gut barrier function and health. Despite its biomedical relevance, the genomic diversity of A. muciniphila remains understudied and that of closely related species, except for A. glycaniphila, unexplored. RESULTS: We present a...
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