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Genomic analysis of Enterococcus faecium co-carrying optrA and poxtA from a swine farm: dissemination across the human–animal–environment interface

8 Jan 2026

Abstract excerpt

BACKGROUND: The transferable resistance genes optrA and poxtA mediate cross-resistance to florfenicol and linezolid, posing serious challenges to both veterinary and human healthcare. Swine farms serve as critical ecological niches for the development and dissemination of multidrug-resistant (MDR) Enterococcus faecium (E. faecium) strains. However, the mechanisms by which E. faecium harboring optrA and poxtA...

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PMID: 41501627
DOI: 10.1186/s12866-025-04666-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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