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Article

Efficacy and Safety of Firmonertinib Plus Anlotinib as First-Line Treatment for Advanced NSCLC With EGFR Mutations: A Single-Arm, Phase I/II Trial.

Clinical lung cancer - 1 Apr 2026

Shi Huiyang, Zhu Haohua, Tang Le, Lu Jingyu, Zhu Kai, Wang Miaohan, Hu Xingsheng, Shi Yuankai

Abstract excerpt

BACKGROUND: This single-arm, phase I/II trial aimed to evaluate the efficacy and safety of firmonertinib plus anlotinib as first-line treatment for patients with non small-cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations. METHODS: We enrolled patients aged 18 years or older and had locally advanced or metastatic NSCLC harboring EGFR sensitive mutation. Patients were treated...

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Identifiers

PMID: 41500871
DOI: 10.1016/j.cllc.2025.11.010

Genes

EGFR
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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