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Comparison of efficacy and safety of second- and third-generation TKIs for non-small-cell lung cancer with uncommon EGFR mutations.

Cancer medicine - 1 Aug 2023

Hao Yue, Xu Manyi, Jin Jianan, Si Jinfei, Xu Chunwei, Song Zhengbo

Abstract excerpt

BACKGROUND: The efficacy of definite for non-small-cell lung cancer (NSCLC) with uncommon epidermal growth factor receptor (EGFR) mutations has been preliminarily demonstrated. However, there is a paucity of data with which to compare the efficacy and safety of second- and third-generation TKIs in patients with NSCLC carrying uncommon EGFR mutations. METHODS: We compared the efficacy and safety of second- and...

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Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Lung Neoplasms
Mutation
Protein Kinase Inhibitors

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Treatment Outcome

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PMID: 37306192
DOI: 10.1002/cam4.6229
PMCID: PMC10469645

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