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Article

QTL fine mapping and functional analysis reveal rs325845933 in the 3'UTR of RPS6KB1 as a putative functional mutation affecting litter size in Erhualian pigs.

International journal of biological macromolecules - 1 Jan 2026

Jiang Nengjing, Ni Mengru, Zhou Tianwei, Zhang Qian, Yin Yanzhen, Xiao Xuemei, Chen Yuejia, Liao Xing, Ai Xinjie, Huang Yuan, Hong Yaqin, Xu Binbin, Zhao Qinqbo, Huang Ruihua, Li Pinghua

Abstract excerpt

Litter size is an important economic trait in the swine industry, and increasing the number of piglets born is a key objective in pig breeding. The Erhualian pig, known for its exceptional prolificacy, has been reported to harbor a quantitative trait locus (QTL) for litter size on porcine chromosome 12 (SSC12). Through fine mapping of this QTL, RPS6KB1 was identified as a promising candidate gene associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41500285
DOI: 10.1016/j.ijbiomac.2025.150006

Genes

RPS6KB1
HSD3B1
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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