Time-dependent diffusion-weighted imaging assessment of tumor grading and isocitrate dehydrogenase genotypes in adult-type diffuse gliomas.

doi:10.1007/s11604-025-01936-w

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Article

Time-dependent diffusion-weighted imaging assessment of tumor grading and isocitrate dehydrogenase genotypes in adult-type diffuse gliomas.

Japanese journal of radiology - 1 May 2026

Kamimura Kiyohisa, Nakano Tsubasa, Nakajo Masanori, Kamizono Junki, Hasegawa Tomohito, Tobo Daiki, Mukai Akie, Kamimura Yoshiki, Ejima Fumitaka, Nagano Hiroaki, Takumi Koji, Nakajo Masatoyo, Higa Nayuta, Yonezawa Hajime, Hanaya Ryosuke, Kirishima Mari, Tanimoto Akihide, Otsuka Hirokazu, Hirahara Daisuke, Imai Hiroshi, Feiweier Thorsten, Yoshiura Takashi

Abstract excerpt

BACKGROUND: This study aimed to investigate the usefulness of time-dependent diffusion magnetic resonance imaging (MRI) parameters compared with the conventional apparent diffusion coefficient (ADC) in distinguishing tumor grade and isocitrate dehydrogenase (IDH) genotypes of adult-type diffuse gliomas. METHODS: This retrospective study included 102 patients with adult-type diffuse gliomas. ADC maps obtained...

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PMID: 41489694
DOI: 10.1007/s11604-025-01936-w
PMCID: PMC13144230

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