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Article

Clinical, manometric, genetic, and histologic associations in pediatric intestinal pseudo-obstruction: A case series.

Journal of pediatric gastroenterology and nutrition - 1 Mar 2026

Wolfson Sharon, Butrviengpunt Myra, Tjaden Naomi, Benitez Alain J, Kota Archana S, Webster Jennifer, Kapavarapu Prasanna, Mousa Hayat, Heuckeroth Robert O

Abstract excerpt

OBJECTIVES: Pediatric intestinal pseudo-obstruction (PIPO) is a severe bowel motility disorder characterized by impaired propulsion of gastrointestinal contents without mechanical obstruction. PIPO encompasses congenital and acquired disorders, including neuropathies, myopathies, and mesenchymopathies. PIPO presents with abdominal distension, bilious vomiting, and severe constipation. Diagnosis is based on...

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Identifiers

PMID: 41479126
DOI: 10.1002/jpn3.70334
PMCID: PMC12964506

Genes

ACTG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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