Article
Variants in the Enteric Smooth Muscle Actin γ-2 Cause Pediatric Intestinal Pseudo-obstruction in Chinese Patients.
Journal of pediatric gastroenterology and nutrition - 1 Jan 2021
Wei Zhiliang, Lu Lina, Zheng Youjie, Yan Weihui, Tao Yijng, Xiao Yongtao, Cai Wei, Wang Ying
Abstract excerpt
OBJECTIVES: Pediatric intestinal pseudo-obstruction (PIPO) is a severe gastrointestinal disorder occurring in children, leading to failure to thrive, malnutrition, and long-term parenteral nutrition dependence. Enteric smooth muscle actin γ-2 (ACTG2) variants have been reported to be related to the pathogenesis of PIPO. This study aimed to determine the presence of ACTG2 variants in Chinese PIPO patients....
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