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Article

Deep learning-based MRI model for predicting P53-mutated hepatocellular carcinoma.

BMC medical imaging - 22 Dec 2025

Jia Lulu, Yang Qing, Jiang Hanchen, Huang Gang, Wang Zhijun, Guo Xinxin, Li Jinkui, Xu Hao, Lei Junqiang

Abstract excerpt

BACKGROUND: The P53-mutated Hepatocellular Carcinoma (HCC) is an aggressive variant associated with vascular endothelial growth factor (VEGF) overexpression and increased microvascular density. This study aimed to develop an MRI-based deep learning model for predicting P53-mutated HCC. METHODS: A total of 312 HCC patients who underwent gadolinium-enhanced MRI and were pathologically confirmed between January 2018...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41430161
DOI: 10.1186/s12880-025-02045-w
PMCID: PMC12723874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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