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A novel MRI-based deep learning networks combined with attention mechanism for predicting CDKN2A/B homozygous deletion status in IDH-mutant astrocytoma.

European radiology - 1 Jan 2024

Zhang Liqiang, Wang Rui, Gao Jueni, Tang Yi, Xu Xinyi, Kan Yubo, Cao Xu, Wen Zhipeng, Liu Zhi, Cui Shaoguo, Li Yongmei

Abstract excerpt

OBJECTIVES: To develop a high-accuracy MRI-based deep learning method for predicting cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) homozygous deletion status in isocitrate dehydrogenase (IDH)-mutant astrocytoma. METHODS: Multiparametric brain MRI data and corresponding genomic information of 234 subjects (111 positives for CDKN2A/B homozygous deletion and 123 negatives for CDKN2A/B homozygous deletion) were...

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PMID: 37553486
DOI: 10.1007/s00330-023-09944-y

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