Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

O06 Complete spontaneous resolution of NRAS-mosaic multiple congenital melanocytic naevi: proof of principle for therapeutic mole reversal.

19 Dec 2025

Abstract excerpt

We present a unique case of complete spontaneous resolution of multiple congenital melanocytic naevi (CMN) with 17 years of photographic, histological and genetic evidence. This case is of biological importance as proof of principle that CMN are not permanent malformations, but rather potentially-reversable lesions. In turn, this proof of principle is of clinical importance, as the increased risk of melanoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and rare skin diseases.
Share to GTP Phosphohydrolases
Share to MAP Kinase Signaling System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Melanoma

Share to Molecular Targeted Therapy

Share to Nevus, Pigmented

Share to Practice Guidelines as Topic

Share to Skin Neoplasms

Source

Identifiers

PMID: 41412987
DOI: 10.1093/bjd/ljaf465.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

O06 Complete spontaneous resolution of NRAS-mosaic multiple congenital melanocytic naevi: proof of principle for therapeutic mole reversal.PMID 41412987Read ↗

Making a Mountain Out of a Molehill: NRAS, Mosaicism, and Large Congenital NeviSemantic proximity Read ↗

Molecular NevogenesisSemantic proximity Read ↗

Congenital melanocytic nevi: update in genetics and management.Semantic proximity Read ↗

Congenital melanocytic naevi: An up-to-date overview.Semantic proximity Read ↗

Melanoma in congenital melanocytic naevi.Semantic proximity Read ↗

NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi.Semantic proximity Read ↗

Hiding in plain sight: molecular genetics applied to giant congenital melanocytic nevi.Semantic proximity Read ↗

An update on congenital melanocytic nevus syndrome: A case report and literature review.Semantic proximity Read ↗

Great Ormond Street Hospital for Children Registry for Congenital Melanocytic Naevi: prospective study 1988-2007. Part 2--Evaluation of treatments.Semantic proximity Read ↗

Congenital melanocytic nevus: two clinicopathological forms.Semantic proximity Read ↗

Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1-epidemiology, phenotype and outcomes.Semantic proximity Read ↗

Rapidly involuting congenital melanocytic naevi in two children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.