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Article

The SynMall resource for characterizing the functional impact of synonymous variation.

Genome research - 3 Feb 2026

Ye Chen, Li Xiaoyan, Cheng Na, Su Yansen, Xia Junfeng

Abstract excerpt

Synonymous single-nucleotide variants (sSNVs) are increasingly recognized as contributors to disease, yet existing variant annotation databases offer limited functional insights for sSNVs. Here, we present SynMall, a comprehensive resource designed to decipher the functional impact of synonymous variation. SynMall catalogs 25 million potential human sSNVs and integrates evolutionary and population information of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41407553
DOI: 10.1101/gr.281257.125
PMCID: PMC12863188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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