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Article

Functional evaluation of NAA10 variants in patients with Ogden syndrome.

Psychiatric genetics - 1 Mar 2026

Aydin Gumus Aydeniz, Dogan Mustafa, Gezdirici Alper, Akbulut Ekrem, Kinay Ermis Duygu

Abstract excerpt

OBJECTIVES: The catalytic subunit of NatA, the main component of the N-terminal acetyltransferase complex, which is involved in most of the acetylation of the human proteome, is encoded by the NAA10 gene. Mutations in the NAA10 gene lead to neurodegenerative diseases associated with disruption of acetylation. Ogden syndrome (OS) is a rare X-linked recessive or dominantly inherited disorder associated with NAA10...

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Identifiers

PMID: 41384780
DOI: 10.1097/YPG.0000000000000409

Genes

NAA10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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