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Article

CD31-associated vascular phenotyping using Doppler ultrasound and dual-energy CT for recurrence risk stratification in papillary thyroid cancer.

Cancer imaging : the official publication of the International Cancer Imaging Society - 10 Dec 2025

Zhou Yan, Xu Feng, Hu Yu, Li Xiao, Si Yan, Su Guoyi, Wu Feiyun, Xu Xiaoquan

Abstract excerpt

BACKGROUND: Angiogenesis plays a pivotal role in PTC aggressiveness and recurrence. CD31, an endothelial marker, provides a histological correlate of tumor vascularity. This study aimed to establish a multimodal imaging framework using Doppler ultrasound (US) and dual-energy CT (DECT) to capture CD31-associated vascular phenotypes for recurrence risk stratification. METHODS: A total of 414 PTC patients (training...

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Topics

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Share to Neoplasm Recurrence, Local
Share to Neovascularization, Pathologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Platelet Endothelial Cell Adhesion Molecule-1

Share to Risk Assessment

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Share to Tomography, X-Ray Computed

Share to Ultrasonography, Doppler

Source

Open in PubMed Open full text

Identifiers

PMID: 41372989
DOI: 10.1186/s40644-025-00975-w
PMCID: PMC12801959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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