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Article

Evaluating the Negative-Strand Coding Potential in Plum Pox Virus.

Molecular plant pathology - 1 Dec 2025

García Beatriz, Del Álamo José Vicente, Rincón Mario, Gonzalo Irene, Cheng Xiaofei, García Juan Antonio, Simón-Mateo Carmen, Valli Adrián A, Rodamilans Bernardo

Abstract excerpt

Recent studies proposed that the negative strands of some single-stranded, positive-sense RNA viruses contain reverse open reading frames (rORFs) that encode functional peptides. Highly conserved rORFs were found in the negative strand of viruses within the Potyviridae family, including turnip mosaic virus (TuMV), where rORF2 was shown to be essential for infection and survival. In this study, we analysed the...

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PMID: 41362096
DOI: 10.1111/mpp.70179
PMCID: PMC12686549

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