Article
Engineering the 3'-UTR of Tobacco Vein Mottling Virus to Confer Cross-Protection Against Potyviruses.
Molecular plant pathology - 1 May 2026
Wang Haijuan, Sun Zhenqi, Zhang Baolong, Wu Zhaoran, Xu Jiaxin, Zhao Mingmin
Abstract excerpt
Tobacco vein mosaic virus (TVMV) is a member of the family Potyviridae. We explored if engineering the 3' noncoding RNA would alter viral infection symptoms and viral infectivity of TVMVwt, which could be used for cross-protection. We engineered an infectious clone of TVMV mutant virus pLX-TVMV58 (TVMV58), which contains a 58-nt 'AT' fragment in the 3'-untranslated region (UTR) of the full-length cDNA infectious...
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