Article
Preoperative stratification of Ki-67 proliferation index in intrahepatic mass-forming cholangiocarcinoma via tumor-halo radiomic phenotyping on biparametric MRI: a multicenter diagnostic model.
BMC medical imaging - 4 Dec 2025
Li Xiaomeng, Xing Lihong, Zhuo Liyong, Xue Linyan, Duan Jitao, Dong Jinghui, Zhang Yanyan, Wang Ximing, Kang Bing, Yin Xiaoping, Li Hongjun
Abstract excerpt
BACKGROUND: Ki-67-driven tumor proliferation influences treatment and prognosis in intrahepatic mass-forming cholangiocarcinoma (IMCC), but preoperative imaging biomarkers for Ki-67 assessment are lacking. This study explores the relationship between Magnetic resonance imaging (MRI) tumor-halo radiomic features, imaging features, and Ki-67 expression levels. METHODS: The preoperative clinical and MRI data of 151...
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