Article
Efficacy and safety of Depemokimab in asthma with eosinophilic phenotype: a systematic review and meta-analysis of randomized controlled trials.
BMC immunology - 3 Dec 2025
Gill Basir Afzaal, Ijaz Anum, Fatima Noor, Ahmed Arsalan, Noor Ayesha, Sharif Samia, Fatima Ishrat, Saeeda Amna, Devi Hansa, Saddique Muhammad Nabeel
Abstract excerpt
INTRODUCTION: Asthma is a complex and heterogeneous disease that significantly impacts quality of life. Eosinophilic asthma, characterized by elevated eosinophil levels, leads to inflammation and hypersensitivity. Many patients remain inadequately managed, resulting in frequent exacerbations and hospitalizations despite standard treatment options. Depemokimab, a long-acting monoclonal antibody that targets IL-5,...
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