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Article

Unsupervised Coverage Sampling to Enhance Clinical Chart Review Coverage for Computable Phenotype Development: Simulation and Empirical Study.

JMIR medical informatics - 27 Nov 2025

Wang Zigui, Hurst Jillian H, Hong Chuan, Goldstein Benjamin Alan

Abstract excerpt

Background: Developing computable phenotypes (CP) based on electronic health records (EHR) data requires "gold-standard" labels for the outcome of interest. To generate these labels, clinicians typically chart-review a subset of patient charts. Charts to be reviewed are most often randomly sampled from the larger set of patients of interest. However, random sampling may fail to capture the diversity of the...

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Cluster Analysis
Computer Simulation
COVID-19
Electronic Health Records
CP gene

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PMID: 41313165
DOI: 10.2196/72068
PMCID: PMC12661603

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CP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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