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Heterozygous mutation in the SdhD subunit confers resistance to thifluzamide in the multinucleate pathogen Sclerotium rolfsii.

Pest management science - 1 Mar 2026

Jiang Chaofan, Zhou Lin, Cheng Weifeng, He Wenjue, Yang Yue, Cui Kaidi, He Leiming

Abstract excerpt

BACKGROUND: Peanut stem rot, a destructive soil-borne disease caused by the multinucleate fungus Sclerotium rolfsii, is primarily controlled using the succinate dehydrogenase inhibitor (SDHI) fungicide thifluzamide. However, the sensitivity and resistance mechanisms of S. rolfsii to thifluzamide remain unclear. RESULTS: This study determined that thifluzamide exhibits strong inhibitory activity against S. rolfsii...

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PMID: 41247091
DOI: 10.1002/ps.70370

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