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Article

Utilization of the All of Us Research Program in a study of genetics in Yao syndrome.

The Journal of allergy and clinical immunology - 1 Mar 2026

Wu Song, Deng Zuoming, Uddin Asif, Xin Baozhong, Gorevic Peter D, Yao Qingping

Abstract excerpt

BACKGROUND: Yao syndrome (OMIM 617321) is a chronic and recurring inflammatory disease linked to specific variants in the nucleotide-binding oligomerization domain containing protein 2 (NOD2) gene. OBJECTIVE: This study aimed to further dissect the genetic mechanisms of the disease. METHODS: A total of 405 patients suspected of having systemic autoinflammatory diseases were included. Molecular testing was...

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Arthritis
Child
Dermatitis
Fever
Hereditary Autoinflammatory Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nod2 Signaling Adaptor Protein

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PMID: 41207643
DOI: 10.1016/j.jaci.2025.10.028

Genes

NOD2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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