Unveiling meropenem resistance and co-resistance patterns in Klebsiella pneumoniae and Acinetobacter baumannii: a global genome analysis using ML/DL and association mining.

Abstract excerpt

The increasing prevalence of meropenem-resistant gram-negative bacteria has led to higher treatment failure and mortality rates. The global availability of bacterial WGS data with antimicrobial resistance phenotypes enables large-scale analyses to explore resistance determinants. This study investigated meropenem resistance mechanisms in multidrug-resistant Klebsiella pneumoniae (KP) and Acinetobacter baumannii...

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