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Article

Phenotype and Long-Term Outcome in Recurrent Paediatric Acute Liver Failure: Systematic Review and Individual Participant Data Analysis.

Liver international : official journal of the International Association for the Study of the Liver - 1 Nov 2025

Sutton Harry, Saban Or Steg, Cunningham Jessie, Bandsma Robert, Sayed Blayne, Ng Vicky

Abstract excerpt

BACKGROUND AND AIMS: Recurrent acute liver failure (RALF) in children is defined as two or more episodes of acute liver failure with complete recovery in between. Several genetic mutations are associated with this condition, including NBAS, RINT1, LARS1 and SCYL1. We have reported liver transplant and mortality rates to help providers make informed management decisions. METHODS: We conducted a systematic review...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41159810
DOI: 10.1111/liv.70412
PMCID: PMC12571025

Genes

LARS1
NBAS
RINT1
SCYL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Phenotype and Long-Term Outcome in Recurrent Paediatric Acute Liver Failure: Systematic Review and Individual Participant Data Analysis.PMID 41159810Read ↗

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