Article
Metastasizing Ameloblastoma Mimicking Squamous Cell Carcinoma of the Lung and Harboring an AKT1 Mutation.
Head and neck pathology - 27 Oct 2025
Arrich James, Forrest Steven, Lofthouse Matthew, Triantafyllou Asterios, Hunter Keith D, Haragan Alexander
Abstract excerpt
We present a case of a 41-year-old non-smoker male patient presenting with ameloblastoma which metastasized to the lung 14 years post excision of the primary mandibular tumor. A biopsy of the pulmonary mass was initially diagnosed as squamous cell carcinoma by a non-specialist pathologist who was not provided a history of the patient's prior ameloblastoma diagnosis. The patient subsequently underwent neoadjuvant...
Read the complete abstract on PubMedTopics
- Humans
- Male
- Adult
- Lung Neoplasms
- Ameloblastoma
- Mandibular Neoplasms
- Proto-Oncogene Proteins c-akt
