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Article

Rubella-associated granuloma in a patient with a compound heterozygous RAG1 defect and review of the literature.

Immunologic research - 27 Oct 2025

Akarsu Aysegul, Sonmez Gamze, Schiefer Ana-Iris, Ozcan H Nursun, Üner Meral, Esenboga Saliha, Duzova Ali, Oberndorfer Felicitas, Ozen Seza, Ayvaz Mehmet, Özçelik Uğur, Cagdas Deniz

Abstract excerpt

Recombination-activating gene (RAG) 1-2 deficiencies have a phenotype spectrum from severe combined to combined immunodeficiency (CID). We presented a comprehensive immunologic/genetic/radiologic/pathological, and virologic evaluation results of a patient with granuloma and reviewed the medical literature in 2022-2025 period for rubella virus (RuV)-associated granulomas in inborn errors of immunity (IEI). We...

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Adolescent
CD4 gene
RAG1 gene
Granuloma
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homeodomain Proteins

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PMID: 41139764
DOI: 10.1007/s12026-025-09711-9

Genes

RAG1
CD4
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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