Article
No evidence for restriction of Beta-HPV8 gene expression by epidermodysplasia verruciformis susceptibility genes CIB1, TMC6, or TMC8 in keratinocytes.
Tumour virus research - 1 Dec 2025
Rehm Tina M, Parpoulas Christina, Straub Elke, Iftner Thomas, Stubenrauch Frank
Abstract excerpt
Epidermodysplasia verruciformis (EV) is an autosomal recessive disorder characterized by an extraordinary susceptibility to infections with human papillomaviruses (HPV), mainly from the genus beta. EV patients carry biallelic loss-of-function mutations in TMC6 encoding Transmembrane channel-like protein 6 or EV protein 1 (EVER1), TMC8 encoding Transmembrane channel-like protein 8 or EV protein 2 (EVER2), or CIB1...
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