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Article

Molecular Pathogenesis of Joint Hypermobility: The Role of Intergenic Interactions.

Medical sciences (Basel, Switzerland) - 7 Oct 2025

Akhiiarova Karina, Tyurin Anton, Khusainova Rita

Abstract excerpt

Background: Joint hypermobility (JH) is an increase in the range of joint movements beyond physiological limits. To date, there is no common understanding of the pathogenesis of this condition. The aim of the study was to analyze the intergenic interactions of SNPs of candidate genes involved in connective tissue metabolism in order to assess their total contribution to the pathogenesis of JH. Methods: A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41133505
DOI: 10.3390/medsci13040223
PMCID: PMC12550910

Genes

TRPM6
ADAMTS5
GDF5
ACAN
BMP5
GREM2
HJV
LUM
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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