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“To have children or not?” Between desire, responsibility, luck, and guilt: reproductive decision-making in individuals with neurofibromatosis type 1

21 Oct 2025

Abstract excerpt

BACKGROUND: Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disorder with a 50% chance of being passed to offspring. Its hereditary nature presents individuals with complex reproductive dilemmas. This study explores the complexity of decision-making and reproductive choices faced by people with NF1 regarding parenthood. RESULTS: Genetic risk is a key factor shaping reproductive decisions. For some...

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PMID: 41121384
DOI: 10.1186/s13023-025-04061-z

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