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Article

Cardiovascular phenotype analysis in large and abnormal offspring calves in relation to assisted reproductive technology†.

Biology of reproduction - 18 Aug 2026

Louie Elizabeth Williams, Macias Amanda A, Mitchell Katharyn J, Divers Thomas J, Donnelly Callum G

Abstract excerpt

Large offspring syndrome/Abnormal Offspring syndrome (LOS/AOS) occurs at an increased frequency in calves derived from assisted reproductive techniques (ARTs). Specific criteria for LOS diagnosis in calves are lacking. Cardiac and vascular anomalies are common in ART derived neonates but have not been described in calves. Calves derived from in vitro produced (IVP) embryos and referred to Cornell University for...

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Identifiers

PMID: 41074770
DOI: 10.1093/biolre/ioaf223
PMCID: PMC13293166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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