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Review: Large offspring syndrome in ruminants: current status and prediction during pregnancy

1 May 2023

Abstract excerpt

Large/abnormal Offspring Syndrome (LOS/AOS) is a congenital overgrowth condition of cattle and sheep, characterized by macrosomia, abdominal wall defects, organomegaly, difficulty to stand and suckle at parturition. The condition was first described as an exclusive consequence of assisted reproductive technologies, such as in vitro production and somatic cell nuclear transfer (cloning). However, we recently...

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PMID: 37567678
DOI: 10.1016/j.animal.2023.100740

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