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Article

Diagnostic challenges of central compartment atopic disease in type-2 chronic rhinosinusitis.

Acta otorrinolaringologica espanola - 1 Jan 2026

Moreno-Luna Ramón, Vizcarra Melgar Julissa, Martín Jiménez Daniel, Clari Comes Meritxell, Infante Cossio Pedro, Sánchez Gómez Serafín

Abstract excerpt

BACKGROUND: Central compartment atopic disease (CCAD) is an emerging phenotype of type-2 chronic rhinosinusitis (CRS), characterized by inflammation involving the central nasal structures. The absence of standardized diagnostic criteria has hindered its recognition. This study aims to describe the first European cohort of CCAD patients and compare its features with previously published international data....

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PMID: 41057095
DOI: 10.1016/j.otoeng.2025.512290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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