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Article

Defective but tumorigenic: the evolutionary and functional roles of mutated oncoviruses.

FEMS microbiology reviews - 14 Jan 2025

Sato Yoshitaka, Okuno Yusuke, Murata Takayuki, Kimura Hiroshi

Abstract excerpt

Human oncogenic viruses contribute significantly to the global health burden and include seven types: Epstein-Barr virus, hepatitis B virus, human T-cell leukemia virus type 1, human papillomavirus, hepatitis C virus, Kaposi's sarcoma-associated herpesvirus, and Merkel cell polyomavirus. While the roles of latent or integrated viral genomes in cancer have been documented, emerging evidence highlights the...

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Topics

Humans
Oncogenic Viruses
Carcinogenesis
Mutation
Tumor Virus Infections
Neoplasms
Evolution, Molecular

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Identifiers

PMID: 41004261
DOI: 10.1093/femsre/fuaf048
PMCID: PMC12512138

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