Genomic diversity of the African malaria vector Anopheles funestus.

doi:10.1126/science.adu3596

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Article

Genomic diversity of the African malaria vector Anopheles funestus.

Science (New York, N.Y.) - 18 Sept 2025

Boddé Marilou, Nwezeobi Joachim, Korlević Petra, Makunin Alex, Akone-Ella Ousman, Barasa Sonia, Gadji Mahamat, Hart Lee, Kaindoa Emmanuel W, Love Katie, Lucas Eric R, Lujumba Ibra, Máquina Mara, Nagi Sanjay C, Odero Joel O, Polo Brian, Sangbakembi Claire, Dadzie Samuel, Koekemoer Lizette L, Kwiatkowski Dominic, McAlister Erica, Ochomo Eric, Okumu Fredros, Paaijmans Krijn, Tchouassi David P, Wondji Charles S, Ayala Diego, Durbin Richard, Miles Alistair, Lawniczak Mara K N

Abstract excerpt

Anopheles funestus s.s. is a major human malaria vector across Africa. To study its evolution, especially under vector control pressure, we sequenced 656 modern specimens (collected 2014 to 2018) and 45 historic specimens (collected 1927 to 1967) from 16 African countries. Despite high genetic diversity, the species shows stable but considerable continental population structure. Although one population showed...

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PMID: 40966334
DOI: 10.1126/science.adu3596

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