Whole exome sequencing analysis of suicidal thoughts and behaviors in a veteran cohort implicates inflammatory pathways and genes previously associated with psychiatric and neurodegenerative diseases.

Abstract excerpt

BACKGROUND: Suicide is a leading cause of death among younger veterans; however, the genetic basis of suicide remains largely unknown. While prior genome-wide association studies (GWAS) have identified common variants associated with suicidal ideation and attempts, a pressing need remains for unbiased assessment of rare and coding genetic variation with respect to suicide phenotypes. METHODS: Here, we conducted...

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