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Unmapped reads from whole-genome sequencing data reveal pathogen diversity in European and African cattle breeds.

Genomics - 1 Nov 2025

Ruvinskiy Daniil, Pokharel Kisun, Okwasiimire Rodney, Gonzalez-Prendes Rayner, Ginja Catarina, Ghanem Nasser, Kugonza Donald R, Makgahlela Mahlako L, Lindeberg Heli, Weldenegodguad Melak, Kantanen Juha, Derks Martijn, Crooijmans Richard P M A

Abstract excerpt

Climate change is impacting the global spread of infectious diseases, altering pathogen distribution and transmission, and threatening human and animal health. This study investigates the presence of potential pathogens in blood within unmapped reads obtained from whole-genome sequencing (WGS) data of various cattle breeds across geographically diverse regions, including South Africa, Uganda, Egypt, Portugal, The...

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PMID: 40939771
DOI: 10.1016/j.ygeno.2025.111108

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