Article
Novel Genetic Loci for Nontuberculous Mycobacterial Pulmonary Disease and Potential Protective Effect of Body Mass Index.
American journal of respiratory and critical care medicine - 1 Nov 2025
Park Kyungtaek, Kim Hyejin, Huh Hee Jae, Namkoong Ho, Hasegawa Naoki, Nishimura Tomoyasu, Asakura Takanori, Morimoto Kozo, Kurashima Atsuyuki, Omae Yosuke, Kawai Yosuke, Tokunaga Katsushi, Berghout Joanne, Fennelly Kevin P, Holland Steven M, Cho Jaeyoung, Yim Jae-Joon, Won Sungho, Jhun Byung Woo, Won Hong-Hee
Abstract excerpt
Rationale: Although nontuberculous mycobacteria (NTM) are widespread, only some individuals develop NTM pulmonary disease (NTM-PD), suggesting the involvement of host factors. Objectives: To identify the genomic structure of NTM-PD and determine whether a definitive association exists between NTM-PD and nine risk factors. Methods: We performed genome-wide association studies in two independent Korean cohorts...
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