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Bioinformatics Analysis Highlight Differentially Expressed CCNB1 and PLK1 Genes as Potential Anti-Breast Cancer Drug Targets and Prognostic Markers

7 Apr 2022

Abstract excerpt

Breast cancer is one of the most common malignant tumors in women worldwide. Early diagnosis, treatment, and prognosis of breast cancer are global challenges. Identification of valid predictive diagnosis and prognosis biomarkers and drug targets are crucial for breast cancer prevention. This study characterizes differentially expressed genes (DEGs) based on the TCGA database by using DESeq2, edgeR, and limma. A...

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Bioinformatics and Genomic Networks
Ferroptosis and cancer prognosis
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35456460
DOI: 10.3390/genes13040654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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