Fifty Shades of Risk: Population Studies and the Genetic Architecture of Kidney Diseases.

Abstract excerpt

Genetics is transforming medicine, providing the possibility of highly specific diagnoses, which in turn allow molecularly defined cohort studies that facilitate detailed insights into gene-specific or even variant-specific prognosis and treatments. Yet, our understanding of genetic variation is changing. Previously, genetic testing typically resulted in a binary result, where an underlying genetic cause was...

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