Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.

Frontiers in bioscience (Landmark edition) - 30 Aug 2025

Zhang Lulin, Chen Wei, Huang Weibin, Cheng Haoling

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is an extremely aggressive brain tumor, marked by restricted therapeutic possibilities and a generally unfavorable prognosis. GBM's complexity and heterogeneity necessitate comprehensive genetic and immunological profiling to enhance therapeutic strategies. METHODS: The study integrated The Cancer Genome Atlas (TCGA) and Integrative Epidemiology Unit Open Genome-Wide Association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Ferroptosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genome-Wide Association Study

Share to Glioblastoma

Share to Mendelian Randomization Analysis

Share to Prognosis

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 40917066
DOI: 10.31083/FBL42844

Genes

RRAS
DCTD
FSTL1
FXYD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.PMID 40917066Read ↗

A Ferroptosis‐Related Prognostic Risk Score Model to Predict Clinical Significance and Immunogenic Characteristics in Glioblastoma MultiformeSemantic proximity Read ↗

Characterization of ferroptosis signature to evaluate the predict prognosis and immunotherapy in glioblastomaSemantic proximity Read ↗

Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experimentsSemantic proximity Read ↗

Identification and Validation of an 11-Ferroptosis Related Gene Signature and Its Correlation With Immune Checkpoint Molecules in GliomaSemantic proximity Read ↗

Enhancing the Understanding of Ferroptosis Mechanisms in Glioblastoma: An Integrated Approach Utilizing Single-Cell Sequencing and Mendelian Randomization MethodsSemantic proximity Read ↗

Identification of Ferroptosis-Related Biomarkers for Prognosis and Immunotherapy in Patients With GliomaSemantic proximity Read ↗

A novel DNA damage and repair-related gene signature to improve predictive capacity of overall survival for patients with gliomas.Semantic proximity Read ↗

Pan-cancer integrated bioinformatics analysis reveals cuproptosis related gene FDX1 is a potential prognostic and immunotherapeutic biomarker for lower-grade gliomasSemantic proximity Read ↗

Prognostic Prediction Model for Glioblastoma: A Ferroptosis-Related Gene Prediction Model and Independent External ValidationSemantic proximity Read ↗

Identification of a Novel Eight-Gene Risk Model for Predicting Survival in Glioblastoma: A Comprehensive Bioinformatic AnalysisSemantic proximity Read ↗

Molecular subtyping of glioblastoma based on immune-related genes for prognosisSemantic proximity Read ↗

Identification of a copper metabolism‐related gene signature for predicting prognosis and immune response in gliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.