Article
Genetic predisposition to persistent fatigue after a diagnosis of colorectal cancer.
Journal of the National Cancer Institute - 1 Dec 2025
Kazemian Elham, Mo Qianxing, Matejcic Marco, Tsai Ya-Yu, Sobieski Daniel, Li Xiaoyin, Hoogland Aasha I, Crowder Sylvia L, Gonzalez Brian D, Oswald Laura B, Sleight Alix G, Nguyen Nathalie, Loroña Nicole C, Damerell Victoria, Komrokji Khaled R, Mooney Kathi, Playdon Mary C, Ulrich Cornelia M, Li Christopher I, Shibata David, Toriola Adetunji T, Ose Jennifer, Peoples Anita R, Hardikar Sheetal, Kahlert Christoph, Siegel Erin M, Bower Julienne E, Schmit Stephanie L, Gigic Biljana, Jim Heather S L, Figueiredo Jane C
Abstract excerpt
BACKGROUND: Cancer-related fatigue (fatigue) is a common and persistent symptom after cancer treatment, yet the role of genetic susceptibility remains unclear. METHODS: We used data from a prospective cohort study called the ColoCare Study, conducted over 5 US sites and Germany. Fatigue was assessed at 5 time points using the European Organisation for the Research and Treatment of Cancer Core Quality of Life...
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