Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Response of primary mammary epithelial cells to pathogen challenge in dairy cows with divergent genomic breeding values for udder health.

Genomics - 1 Sept 2025

Iso-Touru Terhi, Fischer Daniel, Panitz Frank, Taponen Suvi, Cai Zexi, Sahana Goutam, Tapio Ilma, Vilkki Johanna

Abstract excerpt

This study focuses on the initial cellular response to a causal pathogen in the mammary gland of dairy cows aiming to uncover genomic features associated with mastitis resistance. We analyzed transcriptomes from Escherichia coli -challenged primary bovine mammary epithelial cells derived from milk of cows with high or low genomic index value for udder health. The most striking difference was the markedly higher...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breeding
Share to Cattle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to Epithelial Cells

Share to Escherichia coli Infections

Share to Mammary Glands, Animal

Share to Mastitis, Bovine

Share to Transcriptome

Source

Identifiers

PMID: 40876796
DOI: 10.1016/j.ygeno.2025.111102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Response of primary mammary epithelial cells to pathogen challenge in dairy cows with divergent genomic breeding values for udder health.PMID 40876796Read ↗

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle.Semantic proximity Read ↗

Comparative expression profiling of E. coli and S. aureus inoculated primary mammary gland cells sampled from cows with different genetic predispositions for somatic cell score.Semantic proximity Read ↗

Genetic factors affecting susceptibility to udder pathogens.Semantic proximity Read ↗

Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle.Semantic proximity Read ↗

Development of a new tool based on gene expression analyses of bovine raw milk to monitor the inflammatory status of the udderSemantic proximity Read ↗

Genome-Wide Analysis of LncRNA in Bovine Mammary Epithelial Cell Injuries Induced by Escherichia Coli and Staphylococcus AureusSemantic proximity Read ↗

Identification of an immune modulation locus utilising a bovine mammary gland infection challenge model.Semantic proximity Read ↗

Mammary gene expression profiles during an intramammary challenge reveal potential mechanisms linking negative energy balance with impaired immune response.Semantic proximity Read ↗

Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.Semantic proximity Read ↗

Associations between Circulating IGF-1 Concentrations, Disease Status and the Leukocyte Transcriptome in Early Lactation Dairy CowsSemantic proximity Read ↗

Effect of Holstein genotype on immune response to an intramammary Escherichia coli challenge.Semantic proximity Read ↗

Cows selected for divergent mastitis susceptibility display a differential liver transcriptome profile after experimental Staphylococcus aureus mammary gland inoculation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.