c-Fos Mediates Preeclampsia Through p-AMPK/Detyrosinated Tubulin Pathway

Abstract excerpt

BACKGROUND: Preeclampsia is a systemic disorder unique to pregnancy that is associated with trophoblast dysfunction. Although the c-Fos (Fos proto-oncogene) is essential for placental development, its mechanistic role in preeclampsia remains unclear. METHODS: We identified c-Fos as a hub gene through an analysis of cell-free RNA from maternal plasma and single-cell RNA sequencing of preeclamptic placentas. We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pregnancy and preeclampsia studies
• Share to Prenatal Screening and Diagnostics
• Share to Reproductive System and Pregnancy