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Genome-wide selective sweep analysis in high-altitude Changthangi goats reveals candidate genes for pashmina fiber production.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2025

Parsad Ram, Ahlawat Sonika, Vasu Mahanthi, Chhabra Pooja, Sharma Upasna, Arora Reena, Sharma Rekha

Abstract excerpt

Domestic goats (Capra hircus) are vital to global agriculture, with over one billion animals supporting smallholder farmers worldwide. Among goat breeds, the Changthangi goat, native to the trans-Himalayan region of Ladakh, produces pashmina, one of the finest natural fibers (12-16 μm diameter), renowned for its softness and insulation. This study presents the first comprehensive whole-genome comparative analysis...

Topics

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Altitude
Breeding
BMP2 gene
SMAD3 gene
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Selection, Genetic

Source

Identifiers

PMID: 40815313
DOI: 10.1007/s00335-025-10155-7

Genes

COL1A2
ADCY4
BMP2
FGF5
FST
ITGA4
RPS6KB1
SMAD3
SMAD7
WNT9B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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