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Article

Diagnostic Performance and Kinetics of Hepatitis E Viral RNA and IgM Antibody Test Positivity in a Genotype 1 Outbreak in South Sudan.

The Journal of infectious diseases - 17 Jan 2026

Koyuncu Aybüke, Nesbitt Robin C, Alvarez Catia, Asilaza Kinya Vincent, Wamala Joseph, Haile Melat, Gignoux Etienne, Albela Manuel, Gurley Emily S, Loro Frederick Beden, Biem Duol, Rull Monica, Rumunu John, Ciglenecki Iza, Eckerle Isabella, Azman Andrew S

Abstract excerpt

BACKGROUND: Diagnostics are essential for understanding hepatitis E epidemiology, but the field performance of available tests remains unclear. We evaluated the performance of polymerase chain reactions (PCR), IgM ELISA, and the Assure hepatitis E virus (HEV) IgM rapid diagnostic test (RDT) during a HEV genotype 1 outbreak and assessed the duration of viremia and antibodies responses. METHODS: We used data from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40811666
DOI: 10.1093/infdis/jiaf436
PMCID: PMC12811865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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