The 2023 South Sudanese outbreak of Hepatitis E emphasizes ongoing circulation of genotype 1 in North, Central, and East Africa.

doi:10.1016/j.meegid.2024.105667

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The 2023 South Sudanese outbreak of Hepatitis E emphasizes ongoing circulation of genotype 1 in North, Central, and East Africa.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2024

Orf Gregory S, Bbosa Nicholas, Berg Michael G, Downing Robert, Weiss Sonja L, Ssemwanga Deogratius, Ssekagiri Alfred, Ashraf Shirin, da Silva Filipe Ana, Kiiza Ronald, Buule Joshua, Namagembe Hamidah Suubi, Nabirye Stella Esther, Kayiwa John, Deng Lul Lojok, Wani Gregory, Maror James A, Baguma Andrew, Mogga Juma J H, Kamili Saleem, Thomson Emma C, Kaleebu Pontiano, Cloherty Gavin A

Abstract excerpt

In April 2023, an outbreak of acute hepatitis was reported amongst internally displaced persons in the Nazareth community of South Sudan. IgM serology-based screening suggested the likely etiologic agent to be Hepatitis E virus (HEV). In this study, plasma specimens collected from anti-HEV IgM-positive cases were subjected to additional RT-qPCR testing and sequencing of extracted nucleic acids, resulting in the...

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PMID: 39251076
DOI: 10.1016/j.meegid.2024.105667
PMCID: PMC11413618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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